Introduction

Microtubules are cytoskeletal elements, which serve as rails for intracellular transport. We are interested in how the organisation of microtubule network is controlled and how the motility of different cargos is regulated. Our research is focussed on microtubule plus end tracking proteins (+TIPs) - a group of microtubule-associated factors, which bind specifically to the tips of growing microtubules. We investigate the role of these proteins in regulating microtubule dynamics and microtubule association with various cellular structures. We also study the mechanisms of targeting of microtubule-based motors to membrane organelles and the signalling pathways, which control motor activity.

Postdoctoral Positions Available!

We are looking for talented and motivated postdoctoral candidates who are interested in studying cytoskeletal dynamics and intracellular transport.

The general areas of interest for postdoctoral fellows are:

• Biochemistry: Candidates with expertise in protein biochemistry including protein purification and proteomics-based techniques such as mass spectrometry.
• Cell Biology: live-cell fluorescent imaging with an interest in cellular mechanisms of cell motility, protein trafficking, organelle transport and microtubule dynamics.
• Imaging and Biophysics: Candidates with backgrounds in physical science with an interest in developing and applying optical imaging techniques at the cellular level or for in vitro assays.

If you are interested, please submit your curriculum vitae and a letter of motivation to:

EMC Dept. of Cell Biology   EMC Cell Biology Research groups   EMC Medical Genetics

Last update: January 25, 2010